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Thursday, May.2, 2024
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| miRNA: |
hsa-let-7d |
| Disease: |
pancreatic cancer |
Relationship type: |
Unspecified |
Detection method for miRNA expression: |
Northern blot, qRT-PCR etc |
| Expression pattern of miRNA: |
up-regulated |
Validated targets of miRNA from the reference: |
unknown |
Validated targets of miRNA from TarBase: |
unknown : More... |
| Predicted targets: |
MIRANDA, TARGETSCAN, PICTAR-VERT |
Description: Aberrantly expressed miRNA precursors in pancreatic adenocarcinoma.PAM testing was conducted on 10 tumor samples and 15 adjacent benign samples. PAM has correctly classified 100% of the tested tumor samples and 11 of 15 of the tested benign samples. The 20 top ranked differentially expressed miRNAs in pancreatic adenocarcinoma as selected by PAM. |
Reference:
Expression profiling identifies microRNA signature in pancreatic cancer. | PMID:17149698
Lee EJ, Gusev Y, Jiang J, Nuovo GJ, Lerner MR, Frankel WL, Morgan DL, Postier RG, Brackett DJ, Schmittgen TD.
Int J Cancer. 2007 Mar 1;120(5):1046-54. |
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