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Saturday, Apr.20, 2024
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| miRNA: |
hsa-miR-222 |
| Disease: |
papillary thyroid carcinoma (PTC) |
Relationship type: |
Unspecified |
Detection method for miRNA expression: |
Northern blot, qRT-PCR etc |
| Expression pattern of miRNA: |
up-regulated |
Validated targets of miRNA from the reference: |
unknown |
Validated targets of miRNA from TarBase: |
KIT : More... |
| Predicted targets: |
MIRANDA, TARGETSCAN, PICTAR-VERT |
Description: Preliminary analysis of 6 miRNAs in 10 papillary thyroid carcinoma and 10 follicular adenoma identified significant overexpression of miR-146b, -221, and -222 in papillary thyroid carcinoma (P<0.02), but not miR-146a, -155, or -187 (P>0.08). particularly miR-146b, might potentially be adjunct markers for diagnosing papillary thyroid carcinoma in both FNA and surgical pathology specimens. |
Reference:
MicroRNA analysis as a potential diagnostic tool for papillary thyroid carcinoma. | PMID:18587330
Chen YT, Kitabayashi N, Zhou XK, Fahey TJ 3rd, Scognamiglio T.
Mod Pathol. 2008 Jun 27. [Epub ahead of print] |
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