Friday, Mar.29, 2024
miRNA:

hsa-miR-323

Disease:

uterine leiomyoma (ULM)

Relationship type:

Unspecified

Detection method for miRNA expression:

Northern blot, qRT-PCR etc

Expression pattern of miRNA:

up-regulated

Validated targets of miRNA from the reference:

unknown

Validated targets of miRNA from TarBase:

unknown : More...

Predicted targets: MIRANDA, TARGETSCAN, PICTAR-VERT

 

Description:

Real-time reverse transcriptase polymerase chain reaction (RT-PCR) validation of microarray. Realtime semiquantitative RT-PCR of five different microRNA species (miR-21, miR-34a, miR-125b, miR-139, and miR-323) across ten subjects. miR-21, miR-34a, miR-125b, and miR-323 were overexpressed in leiomyoma in the ten pairs tested and miR-139 was underexpressed, consistent with the microarray results.

 

 

Reference:

Differential expression of microRNA species in human uterine leiomyoma versus normal myometrium. | PMID:17765232
Marsh EE, Lin Z, Yin P, Milad M, Chakravarti D, Bulun SE.
Fertil Steril. 2008 Jun;89(6):1771-6. Epub 2007 Sep 4.

 

 
 
 
  miRBase
  Tarbase
  miRGen
  miRGator
  CCBB
  MicroRNA.org
  miRRim
  miRNAMap 2.0
 
 
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