hsa-let-7a

colorectal cancer

Relationship type:

Unspecified

Detection method for miRNA expression:

Northern blot, qRT-PCR etc

down-regulated

Validated targets of miRNA from the reference:

unknown

Validated targets of miRNA from TarBase:

NF2 : More...

Description:

The expression of let-7 miRNA in tumour tissues was considerably down-regulated by over 90% in two of the eight patients compared with the expression in adjacent normal tissues from the same patient.

Reference:

Detection of let-7a microRNA by real-time PCR in colorectal cancer: a single-centre experience from China. | PMID:17944059
Fang WJ, Lin CZ, Zhang HH, Qian J, Zhong L, Xu N.
J Int Med Res. 2007 Sep-Oct;35(5):716-23.