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Thursday, May.2, 2024
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| miRNA: |
hsa-miR-335 |
| Disease: |
breast cancer |
Relationship type: |
Causal |
Detection method for miRNA expression: |
Northern blot, qRT-PCR etc |
| Expression pattern of miRNA: |
down-regulated |
Validated targets of miRNA from the reference: |
SOX4 |
Validated targets of miRNA from TarBase: |
unknown : More... |
| Predicted targets: |
MIRANDA, TARGETSCAN, PICTAR-VERT |
Description: miR-335 regulates a set of genes whose collective expression in a large cohort of human tumours is associated with risk of distal metastasis. |
Reference:
Endogenous human microRNAs that suppress breast cancer metastasis. | PMID:18185580
Tavazoie SF, Alarcon C, Oskarsson T, Padua D, Wang Q, Bos PD, Gerald WL, Massague J.
Nature. 2008 Jan 10;451(7175):147-52. |
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