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Thursday, Apr.25, 2024
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miRNA: |
hsa-miR-342 |
Disease: |
acute promyelocytic leukemia (APL) |
Relationship type: |
Unspecified |
Detection method for miRNA expression: |
microarray |
Expression pattern of miRNA: |
up-regulated |
Validated targets of miRNA from the reference: |
unknown |
Validated targets of miRNA from TarBase: |
unknown : More... |
Predicted targets: |
MIRANDA, TARGETSCAN, PICTAR-VERT |
Description: Upregulation of miR-15a,miR-15b, miR-16-1, let-7a-3, let-7c, let-7d, miR-223,miR-342 and miR-107, whereas miR-181b was downregulated in in acute promyelocytic leukemia patients and cell lines during all-trans-retinoic acid (ATRA) treatment. |
Reference:
MicroRNA gene expression during retinoic acid-induced differentiation of human acute promyelocytic leukemia. | PMID:17260024
Garzon R, Pichiorri F, Palumbo T, Visentini M, Aqeilan R, Cimmino A, Wang H, Sun H, Volinia S, Alder H, Calin GA, Liu CG, Andreeff M, Croce CM.
Oncogene. 2007 Jun 14;26(28):4148-57. Epub 2007 Jan 29. |
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