Wednesday, Apr.24, 2024
miRNA:

hsa-miR-34b
Disease:

ovarian cancer (OC)

Relationship type:

Causal

Detection method for miRNA expression:

Northern blot, qRT-PCR etc
Expression pattern of miRNA:

down-regulated

Validated targets of miRNA from the reference:

unknown

Validated targets of miRNA from TarBase:

unknown : More...
Predicted targets: MIRANDA, TARGETSCAN, PICTAR-VERT

 

Description:

miR-34b and miR-34c are direct targets of p53. miR-34b and miR-34c cooperate in suppressing proliferation and soft-agar colony formation of neoplastic epithelial ovarian cells.

 

 

Reference:

MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth. | PMID:17823410
Corney DC, Flesken-Nikitin A, Godwin AK, Wang W, Nikitin AY.
Cancer Res. 2007 Sep 15;67(18):8433-8. Epub 2007 Sep 6.

 
 
 
 
　 miRBase
　 Tarbase
　 miRGen
　 miRGator
　 CCBB
　 MicroRNA.org
　 miRRim
  miRNAMap 2.0
 
 
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