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Friday, Apr.19, 2024
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| miRNA: |
hsa-miR-375 |
| Disease: |
pancreatic ductal adenocarcinoma (PDAC) |
Relationship type: |
Unspecified |
Detection method for miRNA expression: |
microarray |
| Expression pattern of miRNA: |
down-regulated |
Validated targets of miRNA from the reference: |
unknown |
Validated targets of miRNA from TarBase: |
Adipor2,C1qbp,Jak2,Mtpn,Usp1 : More... |
| Predicted targets: |
MIRANDA, TARGETSCAN, PICTAR-VERT |
Description: differentially expressed between normal and PDAC or cell line samples. several miRNAs(hsa-miR-141, -148a, -200a, -200b, -200c, -216, -217 and -375) with expression patterns distinctive for pancreas, suggesting a possible role of these miRNAs in pancreas differentiation.
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Reference:
MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma. | PMID:17237814
Szafranska AE, Davison TS, John J, Cannon T, Sipos B, Maghnouj A, Labourier E, Hahn SA.
Oncogene. 2007 Jun 28;26(30):4442-52. Epub 2007 Jan 22. |
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