Sunday, May.5, 2024
miRNA:

hsa-miR-181a

Disease:

acute myeloid leukemia (AML)

Relationship type:

Unspecified

Detection method for miRNA expression:

Northern blot, qRT-PCR etc

Expression pattern of miRNA:

up-regulated

Validated targets of miRNA from the reference:

unknown

Validated targets of miRNA from TarBase:

unknown : More...

Predicted targets: MIRANDA, TARGETSCAN, PICTAR-VERT

 

Description:

miR-181a correlated strongly with the AML morphological sub-type and with the expression of genes previously identified through sequence analysis as potential interaction targets,suggesting the direct regulation at transcript level.

 

 

Reference:

MicroRNA miR-181a correlates with morphological sub-class of acute myeloid leukaemia and the expression of its target genes in global genome-wide analysis. | PMID:17330104
Debernardi S, Skoulakis S, Molloy G, Chaplin T, Dixon-McIver A, Young BD.
Leukemia. 2007 May;21(5):912-6. Epub 2007 Mar 1.

 

 
 
 
  miRBase
  Tarbase
  miRGen
  miRGator
  CCBB
  MicroRNA.org
  miRRim
  miRNAMap 2.0
 
 
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