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Monday, Apr.29, 2024
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| miRNA: |
hsa-miR-181a |
| Disease: |
glioblastoma |
Relationship type: |
Unspecified |
Detection method for miRNA expression: |
Northern blot, qRT-PCR etc |
| Expression pattern of miRNA: |
down-regulated |
Validated targets of miRNA from the reference: |
unknown |
Validated targets of miRNA from TarBase: |
unknown : More... |
| Predicted targets: |
MIRANDA, TARGETSCAN, PICTAR-VERT |
Description: The strong down-regulation of miR-128 and miR-181 family might indicate some non-random correlation with the de-differentiated state of tumor cells, or even with their stem-like nature, in some way resembling early embryonic stages. |
Reference:
Extensive modulation of a set of microRNAs in primary glioblastoma. | PMID:16039986
Ciafre SA, Galardi S, Mangiola A, Ferracin M, Liu CG, Sabatino G, Negrini M, Maira G, Croce CM, Farace MG.
Biochem Biophys Res Commun. 2005 Sep 9;334(4):1351-8. |
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