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Sunday, May.19, 2024
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miRNA: |
hsa-miR-1 |
Disease: |
Cerebellar neurodegeneration |
Relationship type: |
Unspecified |
Detection method for miRNA expression: |
Northern blot, qRT-PCR etc |
Expression pattern of miRNA: |
down-regulated |
Validated targets of miRNA from the reference: |
unknown |
Validated targets of miRNA from TarBase: |
GJA1,Hand2,HDAC4,TMSB4X : More... |
Predicted targets: |
MIRANDA, TARGETSCAN, PICTAR-VERT |
Description: Essential for the survival of Purkinje cells and its absence leads to a slow degeneration of these cells. |
Reference:
Cerebellar neurodegeneration in the absence of microRNAs. | PMID:17606634
Schaefer A, O'Carroll D, Tan CL, Hillman D, Sugimori M, Llinas R, Greengard P.
J Exp Med. 2007 Jul 9;204(7):1553-8. Epub 2007 Jul 2. |
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