hsa-miR-125b

anaplastic thyroid carcinoma (ATC)

Relationship type:

Causal

Detection method for miRNA expression:

Northern blot, qRT-PCR etc

down-regulated

Validated targets of miRNA from the reference:

HMGA(HMGA1 and HMGA2)

Validated targets of miRNA from TarBase:

Lin28 : More...

Description:

miR-125b plays a role in slowing the cell proliferation.

Reference:

Specific microRNAs are downregulated in human thyroid anaplastic carcinomas. | PMID:17563749
Visone R, Pallante P, Vecchione A, Cirombella R, Ferracin M, Ferraro A, Volinia S, Coluzzi S, Leone V, Borbone E, Liu CG, Petrocca F, Troncone G, Calin GA, Scarpa A, Colato C, Tallini G, Santoro M, Croce CM, Fusco A.
Oncogene. 2007 Nov 29;26(54):7590-5. Epub 2007 Jun 11.