| miRNA: |
hsa-let-7c |
| Disease: |
prostate cancer |
Relationship type: |
Causal |
Detection method for miRNA expression: |
Northern blot, qRT-PCR etc |
| Expression pattern of miRNA: |
down-regulated |
Validated targets of miRNA from the reference: |
RAS |
Validated targets of miRNA from TarBase: |
unknown : More... |
| Predicted targets: |
MIRANDA, TARGETSCAN, PICTAR-VERT |
Description: let-7c, miR-145 and miR-125b target mRNAs whose proteins have been shown to be increased in prostate cancer. |
Reference:
Widespread deregulation of microRNA expression in human prostate cancer. | PMID:17891175
Ozen M, Creighton CJ, Ozdemir M, Ittmann M.
Oncogene. 2008 Mar 13;27(12):1788-93. Epub 2007 Sep 24. |
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