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Thursday, May.2, 2024
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| miRNA: |
hsa-miR-145 |
| Disease: |
breast cancer |
Relationship type: |
Unspecified |
Detection method for miRNA expression: |
Northern blot, qRT-PCR etc |
| Expression pattern of miRNA: |
down-regulated |
Validated targets of miRNA from the reference: |
unknown |
Validated targets of miRNA from TarBase: |
FLJ21308 : More... |
| Predicted targets: |
MIRANDA, TARGETSCAN, PICTAR-VERT |
Description: A noticeable decrease of miR-145 expression was observed in hyperplastic, probable preneoplastic,ducts present in some of the cases examined. Loss of miR-145 expression is an early event during breast cancer progression, |
Reference:
Altered MicroRNA expression confined to specific epithelial cell subpopulations in breast cancer. | PMID:18089790
Sempere LF, Christensen M, Silahtaroglu A, Bak M, Heath CV, Schwartz G, Wells W, Kauppinen S, Cole CN.
Cancer Res. 2007 Dec 15;67(24):11612-20. |
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