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Friday, May.17, 2024
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| miRNA: |
hsa-miR-145 |
| Disease: |
colorectal cancer |
Relationship type: |
Unspecified |
Detection method for miRNA expression: |
Northern blot, qRT-PCR etc |
| Expression pattern of miRNA: |
down-regulated |
Validated targets of miRNA from the reference: |
unknown |
Validated targets of miRNA from TarBase: |
FLJ21308 : More... |
| Predicted targets: |
MIRANDA, TARGETSCAN, PICTAR-VERT |
Description: miR-143 and miR-145, consistently display reduced steady-state levels of the mature miRNA at the adenomatous and cancer stages of colorectal neoplasia. |
Reference:
Reduced accumulation of specific microRNAs in colorectal neoplasia. | PMID:14573789
Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ.
Mol Cancer Res. 2003 Oct;1(12):882-91. |
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