Thursday, Mar.28, 2024
miRNA:

hsa-miR-145

Disease:

diffuse large B-cell lymphoma (DLBCL)

Relationship type:

Unspecified

Detection method for miRNA expression:

microarray

Expression pattern of miRNA:

down-regulated

Validated targets of miRNA from the reference:

unknown

Validated targets of miRNA from TarBase:

FLJ21308 : More...

Predicted targets: MIRANDA, TARGETSCAN, PICTAR-VERT

 

Description:

Four hsa-miR-As (miR-210, hsa-miR-155, hsa-miR-106a, hsa-miR-17-5p) were expressed at a significantly higher level in DLBCL than in normal tissue. In contrast, the remaining 11 miRNAs (hsa-miR-150, hsa-miR-145, hsa-miR-328, hsa-miR-139, hsa-miR-99a, hsa-miR-10a, hsa-miR-95, hsa-miR-149, hsa-miR-320, hsa-miR-151,let-7e) were expressed at a significantly lower level in DLBCL.

 

 

Reference:

MicroRNA signatures characterize diffuse large B-cell lymphomas and follicular lymphomas. | PMID:18537969
Roehle A, Hoefig KP, Repsilber D, Thorns C, Ziepert M, Wesche KO, Thiere M, Loeffler M, Klapper W, Pfreundschuh M, Matolcsy A, Bernd HW, Reiniger L, Merz H, Feller AC.
Br J Haematol. 2008 Jun 3. [Epub ahead of print]

 

 
 
 
  miRBase
  Tarbase
  miRGen
  miRGator
  CCBB
  MicroRNA.org
  miRRim
  miRNAMap 2.0
 
 
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