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Friday, May.17, 2024
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| miRNA: |
hsa-miR-195 |
| Disease: |
cardiac hypertrophy |
Relationship type: |
Causal |
Detection method for miRNA expression: |
Northern blot, qRT-PCR etc |
| Expression pattern of miRNA: |
up-regulated |
Validated targets of miRNA from the reference: |
unknown |
Validated targets of miRNA from TarBase: |
unknown : More... |
| Predicted targets: |
MIRANDA, TARGETSCAN, PICTAR-VERT |
Description: Cardiac overexpression of miR-195, which was up-regulated during cardiac hypertrophy,
resulted in pathological cardiac growth and heart failure in transgenic mice. |
Reference:
A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure. | PMID:17108080
van Rooij E, Sutherland LB, Liu N, Williams AH, McAnally J, Gerard RD, Richardson JA, Olson EN.
Proc Natl Acad Sci U S A. 2006 Nov 28;103(48):18255-60. Epub 2006 Nov 15. |
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