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Wednesday, Apr.24, 2024
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| miRNA: |
hsa-miR-195 |
| Disease: |
heart failure |
Relationship type: |
Unspecified |
Detection method for miRNA expression: |
Northern blot, qRT-PCR etc |
| Expression pattern of miRNA: |
up-regulated |
Validated targets of miRNA from the reference: |
unknown |
Validated targets of miRNA from TarBase: |
unknown : More... |
| Predicted targets: |
MIRANDA, TARGETSCAN, PICTAR-VERT |
Description: Northern blot analysis of the hypertrophy-regulated miRNAs in idiopathic end-stage failing human hearts showed increased expression of miR-24, miR-125b, miR-195, miR-199a, and miR-214. |
Reference:
A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure. | PMID:17108080
van Rooij E, Sutherland LB, Liu N, Williams AH, McAnally J, Gerard RD, Richardson JA, Olson EN.
Proc Natl Acad Sci U S A. 2006 Nov 28;103(48):18255-60. Epub 2006 Nov 15. |
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