miRNA: |
hsa-miR-196a |
Disease: |
pancreatic ductal adenocarcinoma (PDAC) |
Relationship type: |
Unspecified |
Detection method for miRNA expression: |
Northern blot, qRT-PCR etc |
Expression pattern of miRNA: |
up-regulated |
Validated targets of miRNA from the reference: |
unknown |
Validated targets of miRNA from TarBase: |
unknown : More... |
Predicted targets: |
MIRANDA, TARGETSCAN, PICTAR-VERT |
Description: differentially expressed between normal and PDAC or cell line samples. The mode of expression of miR-196a and -196b is especially interesting. These miRNAs are completely absent in normal and chronic pancreatitis tissues but significantly upregulated in PDAC.
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Reference:
MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma. | PMID:17237814
Szafranska AE, Davison TS, John J, Cannon T, Sipos B, Maghnouj A, Labourier E, Hahn SA.
Oncogene. 2007 Jun 28;26(30):4442-52. Epub 2007 Jan 22. |
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