Description: A cluster of microRNAs was identified as highly expressed in retinoblastoma, including hsa-miR-494, hsa-let-7e, hsa-miR-513-1, hsa-miR-513-2, hsa-miR-518c*, hsa-miR-129-1, hsa-miR-129-2, hsa-miR-198, hsa-miR-492, hsa-miR-498, hsa-miR-320, hsa-miR-503, and hsa-miR-373*. CONCLUSION: These miRNAs are the first to be reported for human retinoblastoma and may play significant roles in regulating tumor genesis. |
Reference:
Identification of miRNAs associated with tumorigenesis of retinoblastoma by miRNA microarray analysis. | PMID:18818933
Zhao JJ, Yang J, Lin J, Yao N, Zhu Y, Zheng J, Xu J, Cheng JQ, Lin JY, Ma X.
Childs Nerv Syst. 2008 Sep 26. [Epub ahead of print] |