Friday, Mar.29, 2024
miRNA:

hsa-miR-129-1

Disease:

retinoblastoma

Relationship type:

Unspecified

Detection method for miRNA expression:

microarray

Expression pattern of miRNA:

up-regulated

Validated targets of miRNA from the reference:

unknown

Validated targets of miRNA from TarBase:

unknown : More...

Predicted targets: MIRANDA, TARGETSCAN, PICTAR-VERT

 

Description:

A cluster of microRNAs was identified as highly expressed in retinoblastoma, including hsa-miR-494, hsa-let-7e, hsa-miR-513-1, hsa-miR-513-2, hsa-miR-518c*, hsa-miR-129-1, hsa-miR-129-2, hsa-miR-198, hsa-miR-492, hsa-miR-498, hsa-miR-320, hsa-miR-503, and hsa-miR-373*. CONCLUSION: These miRNAs are the first to be reported for human retinoblastoma and may play significant roles in regulating tumor genesis.

 

 

Reference:

Identification of miRNAs associated with tumorigenesis of retinoblastoma by miRNA microarray analysis. | PMID:18818933
Zhao JJ, Yang J, Lin J, Yao N, Zhu Y, Zheng J, Xu J, Cheng JQ, Lin JY, Ma X.
Childs Nerv Syst. 2008 Sep 26. [Epub ahead of print]

 

 
 
 
  miRBase
  Tarbase
  miRGen
  miRGator
  CCBB
  MicroRNA.org
  miRRim
  miRNAMap 2.0
 
 
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