| miRNA: |
hsa-miR-183 |
| Disease: |
retinitis pigmentosa (RP) |
Relationship type: |
Unspecified |
Detection method for miRNA expression: |
Northern blot, qRT-PCR etc |
| Expression pattern of miRNA: |
down-regulated |
Validated targets of miRNA from the reference: |
unknown |
Validated targets of miRNA from TarBase: |
unknown : More... |
| Predicted targets: |
MIRANDA, TARGETSCAN, PICTAR-VERT |
Description: expression of miR-96, -182 and -183 decreased by 14.1-53.2%, while expression of miR-1, -133 and -142 was up-regulated by 186.1-538.5%. Significantly, the detected pan-retinal miR signature was mirrored by similar miR expression profiles in FACS-isolated rod photoreceptors from these mice. |
Reference:
Common microRNA signature in mouse models of retinal degeneration. | PMID:18834879
Loscher C, Hokamp K, Humphries P, Farrar GJ, Palfi A.
Exp Eye Res. 2008 Sep 13. [Epub ahead of print] |
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