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Saturday, May.4, 2024
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| miRNA: |
hsa-miR-29c |
| Disease: |
bladder cancer |
Relationship type: |
Unspecified |
Detection method for miRNA expression: |
northern blot, qRT-PCR etc |
| Expression pattern of miRNA: |
down-regulated |
Validated targets of miRNA from the reference: |
unknown |
Validated targets of miRNA from TarBase: |
unknown : More... |
| Predicted targets: |
MIRANDA, TARGETSCAN, PICTAR-VERT |
Description: Here, we showed that up-regulation of miRNA was not commonly found in this limited number of patients, and four miRNAs (miR-26a, miR-29c, miR-30c, miR-30e-5p) were down-regulated as a common marker in patients with a 1-3 grade of disease. Our data suggest that instead of up-regulation of carcinogenic miRNAs, loss of regulation of these miRNA may be critical for bladder tumor development in patients. |
Reference:
Up-regulation of microRNA in bladder tumor tissue is not common. | PMID:19475496
Wang G, Zhang H, He H, Tong W, Wang B, Liao G, Chen Z, Du C.
Int Urol Nephrol. 2009 May 28. [Epub ahead of print] |
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