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Sunday, May.5, 2024
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| miRNA: |
hsa-miR-210 |
| Disease: |
pancreatic cancer |
Relationship type: |
Unspecified |
Detection method for miRNA expression: |
northern blot, qRT-PCR etc |
| Expression pattern of miRNA: |
up-regulated |
Validated targets of miRNA from the reference: |
unknown |
Validated targets of miRNA from TarBase: |
unknown : More... |
| Predicted targets: |
MIRANDA, TARGETSCAN, PICTAR-VERT |
Description: The possible association of microRNA expression and patients' survival was examined using multivariate Cox's regression hazard analyses. Interestingly, significant correlations between elevated microRNA expression and overall survival were observed for miR-155 (RR=2.50; p=0.005), miR-203 (RR=2.21; p=0.017), miR-210 (RR=2.48; p= 0.005) and miR-222 (RR=2.05; p=0.035). Furthermore, tumours from patients demonstrating elevated expression levels of all four microRNAs possessed a 6.2-fold increased risk of tumour-related death compared to patients whose tumours showed a lower expression of these microRNAs. |
Reference:
Elevated expression of microRNAs 155, 203, 210 and 222 in pancreatic tumours associates with poorer survival. | PMID:19551852
Greither T, Grochola L, Udelnow A, Lautenschl?ger C, Würl P, Taubert H.
Int J Cancer. 2009 Jun 23. [Epub ahead of print] |
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