hsa-miR-21

glioma

Relationship type:

Unspecified

Detection method for miRNA expression:

northern blot, qRT-PCR etc

down-regulated

Validated targets of miRNA from the reference:

unknown

Validated targets of miRNA from TarBase:

PTEN,TPM1 : More...

Description:

we identified 12 miRNAs (miR-9, miR-15a, miR-16, miR-17, miR-19a, miR-20a, miR-21, miR-25, miR-28, miR-130b, miR-140 and miR-210) showing increased expression, and two miRNAs (miR-184 and miR-328) showing reduced expression upon progression.

Reference:

Identification and Functional Characterization of microRNAs Involved in the Malignant Progression of Gliomas | PMID:19775293
Malzkorn B, Wolter M, Liesenberg F, Grzendowski M, Stühler K, Meyer HE, Reifenberger G.
Brain Pathol. 2009 Aug 19. [Epub ahead of print]