Thursday, Mar.28, 2024
miRNA:

hsa-miR-21

Disease:

cervical cancer

Relationship type:

Unspecified

Detection method for miRNA expression:

Northern blot, qRT-PCR etc

Expression pattern of miRNA:

up-regulated

Validated targets of miRNA from the reference:

unknown

Validated targets of miRNA from TarBase:

PTEN,TPM1 : More...

Predicted targets: MIRANDA, TARGETSCAN, PICTAR-VERT

 

Description:

let-7b, let-7c, miR-23b, miR-196b, and miR-143 showed significantly reduced abundance in cervical cancer cell lines. miR-21 displayed higher abundance in the cancer group.

 

 

Reference:

Patterns of known and novel small RNAs in human cervical cancer. | PMID:17616659
Lui WO, Pourmand N, Patterson BK, Fire A.
Cancer Res. 2007 Jul 1;67(13):6031-43.

 

 
 
 
  miRBase
  Tarbase
  miRGen
  miRGator
  CCBB
  MicroRNA.org
  miRRim
  miRNAMap 2.0
 
 
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