Thursday, Mar.28, 2024
miRNA:

hsa-miR-21

Disease:

non-alcoholic fatty liver disease (NAFLD)

Relationship type:

Unspecified

Detection method for miRNA expression:

microarray

Expression pattern of miRNA:

down-regulated

Validated targets of miRNA from the reference:

unknown

Validated targets of miRNA from TarBase:

PTEN,TPM1 : More...

Predicted targets: MIRANDA, TARGETSCAN, PICTAR-VERT

 

Description:

Significantly-dysregulated miRNA confirmed by stem-loop RT–PCR between steatotic L02 cells and control.

 

 

Reference:

Effect of miRNA-10b in regulating cellular steatosis level by targeting PPAR-alpha expression, a novel mechanism for the pathogenesis of NAFLD | PMID:19780876
Zheng L, Lv GC, Sheng J, Yang YD.
J Gastroenterol Hepatol. 2009 Sep 25. [Epub ahead of print]

 

 
 
 
  miRBase
  Tarbase
  miRGen
  miRGator
  CCBB
  MicroRNA.org
  miRRim
  miRNAMap 2.0
 
 
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