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Saturday, May.4, 2024
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| miRNA: |
hsa-miR-21 |
| Disease: |
esophageal cancer |
Relationship type: |
Unspecified |
Detection method for miRNA expression: |
microarray |
| Expression pattern of miRNA: |
up-regulated |
Validated targets of miRNA from the reference: |
unknown |
Validated targets of miRNA from TarBase: |
PTEN,TPM1 : More... |
| Predicted targets: |
MIRANDA, TARGETSCAN, PICTAR-VERT |
Description: Both hsa-miR-203 and hsa-miR-205 were expressed 2- to 10-fold lower in squamous cell carcinoma and adenocarcinomas than in normal epithelium. The hsa-miR-21 expression was 3- to 5-fold higher in both tumors than in normal epithelium. |
Reference:
MicroRNA expression profiles of esophageal cancer. | PMID:18242245
Feber A, Xi L, Luketich JD, Pennathur A, Landreneau RJ, Wu M, Swanson SJ, Godfrey TE, Litle VR.
J Thorac Cardiovasc Surg. 2008 Feb;135(2):255-60; discussion 260. Epub 2007 Dec 26. |
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