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Wednesday, Apr.24, 2024
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miRNA: |
hsa-miR-21 |
Disease: |
glioblastoma multiforme (GBM) |
Relationship type: |
Unspecified |
Detection method for miRNA expression: |
Northern blot, qRT-PCR etc |
Expression pattern of miRNA: |
up-regulated |
Validated targets of miRNA from the reference: |
unknown |
Validated targets of miRNA from TarBase: |
PTEN,TPM1 : More... |
Predicted targets: |
MIRANDA, TARGETSCAN, PICTAR-VERT |
Description: Differentially expressed microRNA in glioblastoma multiforme tumors relative to non-neoplastic brain tissue. |
Reference:
miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells. | PMID:18577219
Silber J, Lim DA, Petritsch C, Persson AI, Maunakea AK, Yu M, Vandenberg SR, Ginzinger DG, James CD, Costello JF, Bergers G, Weiss WA, Alvarez-Buylla A, Hodgson JG.
BMC Med. 2008 Jun 24;6:14. |
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