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Wednesday, May.8, 2024
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| miRNA: |
hsa-miR-106a |
| Disease: |
colorectal cancer |
Relationship type: |
Unspecified |
Detection method for miRNA expression: |
Northern blot, qRT-PCR etc |
| Expression pattern of miRNA: |
up-regulated |
Validated targets of miRNA from the reference: |
unknown |
Validated targets of miRNA from TarBase: |
RB1 : More... |
| Predicted targets: |
MIRANDA, TARGETSCAN, PICTAR-VERT |
Description: Expression patterns for these 5 microRNAs(miR-20a, miR-21, miR-106a, miR-181b, and miR-203) distinguish tumor vs paired nontumor status with 96% or 98% accuracy based on 3 nearest neighbors or nearest centroid algorithms, respectively (10-fold cross validation, repeated 100 times). |
Reference:
MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma. | PMID:18230780
Schetter AJ, Leung SY, Sohn JJ, Zanetti KA, Bowman ED, Yanaihara N, Yuen ST, Chan TL, Kwong DL, Au GK, Liu CG, Calin GA, Croce CM, Harris CC.
JAMA. 2008 Jan 30;299(4):425-36. |
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