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Saturday, Apr.20, 2024
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| miRNA: |
hsa-miR-106b |
| Disease: |
Alzheimer's disease |
Relationship type: |
Unspecified |
Detection method for miRNA expression: |
microarray |
| Expression pattern of miRNA: |
down-regulated |
Validated targets of miRNA from the reference: |
unknown |
Validated targets of miRNA from TarBase: |
unknown : More... |
| Predicted targets: |
MIRANDA, TARGETSCAN, PICTAR-VERT |
Description: Significantly changed miRNAs in cortex of sporadic AD cases. |
Reference:
Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression. | PMID:18434550
Hebert SS, Horre K, Nicolai L, Papadopoulou AS, Mandemakers W, Silahtaroglu AN, Kauppinen S, Delacourte A, De Strooper B.
Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6415-20. Epub 2008 Apr 23. |
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