|
|
|
Thursday, Mar.28, 2024
|
|
|
|
|
|
miRNA: |
hsa-miR-1-2 |
Disease: |
cardiomyopathy |
Relationship type: |
Causal |
Detection method for miRNA expression: |
Northern blot, qRT-PCR etc |
Expression pattern of miRNA: |
down-regulated |
Validated targets of miRNA from the reference: |
Irx5, Hand2, Kcnd2 |
Validated targets of miRNA from TarBase: |
unknown : More... |
Predicted targets: |
MIRANDA, TARGETSCAN, PICTAR-VERT |
Description: miR-1-2 regulates cardiac morphogenesis, cardiac conduction, and the cardiac cell cycle. |
Reference:
Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. | PMID:17397913
Zhao Y, Ransom JF, Li A, Vedantham V, von Drehle M, Muth AN, Tsuchihashi T, McManus MT, Schwartz RJ, Srivastava D.
Cell. 2007 Apr 20;129(2):303-17. Epub 2007 Mar 29. |
|
|
|
|
|
|