Thursday, Mar.28, 2024
miRNA:

hsa-miR-1-2

Disease:

cardiomyopathy

Relationship type:

Causal

Detection method for miRNA expression:

Northern blot, qRT-PCR etc

Expression pattern of miRNA:

down-regulated

Validated targets of miRNA from the reference:

Irx5, Hand2, Kcnd2

Validated targets of miRNA from TarBase:

unknown : More...

Predicted targets: MIRANDA, TARGETSCAN, PICTAR-VERT

 

Description:

miR-1-2 regulates cardiac morphogenesis, cardiac conduction, and the cardiac cell cycle.

 

 

Reference:

Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. | PMID:17397913
Zhao Y, Ransom JF, Li A, Vedantham V, von Drehle M, Muth AN, Tsuchihashi T, McManus MT, Schwartz RJ, Srivastava D.
Cell. 2007 Apr 20;129(2):303-17. Epub 2007 Mar 29.

 

 
 
 
  miRBase
  Tarbase
  miRGen
  miRGator
  CCBB
  MicroRNA.org
  miRRim
  miRNAMap 2.0
 
 
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