miRNA: |
hsa-miR-122a |
Disease: |
hepatocellular carcinoma (HCC) |
Relationship type: |
Unspecified |
Detection method for miRNA expression: |
Northern blot, qRT-PCR etc |
Expression pattern of miRNA: |
down-regulated |
Validated targets of miRNA from the reference: |
unknown |
Validated targets of miRNA from TarBase: |
unknown : More... |
Predicted targets: |
MIRANDA, TARGETSCAN, PICTAR-VERT |
Description: miR-122 is an abundant liver-specific miR. miR-122 expressionwas significantly (P=0.013) reduced in 10 out of 20 tumors compared to the pair-matched control tissues. |
Reference:
Downregulation of miR-122 in the rodent and human hepatocellular carcinomas. | PMID:16924677
Kutay H, Bai S, Datta J, Motiwala T, Pogribny I, Frankel W, Jacob ST, Ghoshal K.
J Cell Biochem. 2006 Oct 15;99(3):671-8. |
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