hsa-miR-155

acute myeloid leukemia (AML)

Relationship type:

Unspecified

Detection method for miRNA expression:

Northern blot, qRT-PCR etc

up-regulated

Validated targets of miRNA from the reference:

unknown

Validated targets of miRNA from TarBase:

AGTR1 : More...

Description:

FLT3-ITD samples were characterized by upregulation of miR-155. Further experiments demonstrated that the up-regulation of miR-155 was independent from FLT3 signaling.

Reference:

Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin. | PMID:18308931
Garzon R, Garofalo M, Martelli MP, Briesewitz R, Wang L, Fernandez-Cymering C, Volinia S, Liu CG, Schnittger S, Haferlach T, Liso A, Diverio D, Mancini M, Meloni G, Foa R, Martelli MF, Mecucci C, Croce CM, Falini B.
Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3945-50. Epub 2008 Feb 28.