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Wednesday, May.15, 2024
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| miRNA: |
hsa-miR-183 |
| Disease: |
retinitis pigmentosa (RP) |
Relationship type: |
Unspecified |
Detection method for miRNA expression: |
Northern blot, qRT-PCR etc |
| Expression pattern of miRNA: |
up-regulated |
Validated targets of miRNA from the reference: |
unknown |
Validated targets of miRNA from TarBase: |
unknown : More... |
| Predicted targets: |
MIRANDA, TARGETSCAN, PICTAR-VERT |
Description: Expression of miR-1 and miR-133 decreased by more than 2.5-fold (P<0.001), whereas expression of miR-96 and miR-183 increased by more than 3-fold (P<0.001) in Pro347Ser retinas, as validated by qPCR. |
Reference:
Altered retinal microRNA expression profile in a mouse model of retinitis pigmentosa. | PMID:18034880
Loscher CJ, Hokamp K, Kenna PF, Ivens AC, Humphries P, Palfi A, Farrar GJ.
Genome Biol. 2007;8(11):R248. |
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