hsa-miR-141

homozygous sickle cell disease (HbSS)

Relationship type:

Unspecified

Detection method for miRNA expression:

microarray

down-regulated

Validated targets of miRNA from the reference:

unknown

Validated targets of miRNA from TarBase:

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Description:

Several microRNAs (miR-320, let-7s, miR-181, miR-141) were over-represented in the HbAA erythrocytes, while other microRNAs (miR-29a, miR-144, miR-451, miR-140) were overrepresented in the HbSS erythrocytes.

Reference:

The genomic analysis of erythrocyte microRNA expression in sickle cell diseases. | PMID:18523662
Chen SY, Wang Y, Telen MJ, Chi JT.
PLoS ONE. 2008 Jun 4;3(6):e2360.