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Wednesday, Apr.24, 2024
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| miRNA: |
hsa-miR-200b |
| Disease: |
cholangiocarcinoma |
Relationship type: |
Causal |
Detection method for miRNA expression: |
Northern blot, qRT-PCR etc |
| Expression pattern of miRNA: |
up-regulated |
Validated targets of miRNA from the reference: |
PTPN12 |
Validated targets of miRNA from TarBase: |
unknown : More... |
| Predicted targets: |
MIRANDA, TARGETSCAN, PICTAR-VERT |
Description: inhibition of miR-21 or miR-200b decreased gemcitabine-induced apoptosis. |
Reference:
Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines. | PMID:16762633
Meng F, Henson R, Lang M, Wehbe H, Maheshwari S, Mendell JT, Jiang J, Schmittgen TD, Patel T.
Gastroenterology. 2006 Jun;130(7):2113-29. |
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