|
|
|
|
Thursday, May.16, 2024
|
|
|
|
|
|
| miRNA: |
hsa-miR-200c |
| Disease: |
colorectal cancer |
Relationship type: |
Unspecified |
Detection method for miRNA expression: |
Northern blot, qRT-PCR etc |
| Expression pattern of miRNA: |
up-regulated |
Validated targets of miRNA from the reference: |
unknown |
Validated targets of miRNA from TarBase: |
unknown : More... |
| Predicted targets: |
MIRANDA, TARGETSCAN, PICTAR-VERT |
Description: miR-200c was significantly associated with patient survival (p = 0.0122). The patients (n = 15) with higher hsamiR-200c expression had a shorter survival time (median survival = 26 months) compared to patients(n = 9) with lower expression (median survival = 38 months).miR-200c (p = 0.0322) expression was strongly associated with the mutation status of the p53 tumor suppressor gene. |
Reference:
Prognostic Values of microRNAs in Colorectal Cancer. | PMID:18079988
Xi Y, Formentini A, Chien M, Weir DB, Russo JJ, Ju J, Kornmann M, Ju J.
Biomark Insights. 2006;2:113-121. |
|
|
|
|
|
|
